Publications

Chory lab members designated in bold.

Robotics and PRANCE

  1. Chory EJ*, Wang M*, Ceribelli M, Michalowska AM, Golas S, Beck E, Klumpp-Thomas C, Chen L, McKnight C, Itkin Z, Wilson KM, Holland D, Divakaran S, Bradner J, Khan J, Gryder BE, Thomas CJ, Stanton BZ. High-throughput approaches to uncover synergistic drug combinations in leukemia. SLAS Discov. 2023.

  2. DeBenedictis EA*, Chory EJ*, Gretton DW, Wang B, Golas S, Esvelt KM. Systematic molecular evolution enables robust biomolecule discovery. Nat Methods. 2022.

  3. Chory EJ*, Gretton DW*, DeBenedictis EA, Esvelt KM. Enabling high-throughput biology with flexible open-source automation. Mol Syst Biol. 2021.

Review Articles

  1. Golas S, Chory EJ. Proximity labeling of endogenous protein interactions enabled by directed evolution. Trends Biotechnol. 2023.

  2. Garzón-Porras AM, Chory E, Gryder BE. Dynamic Opposition of Histone Modifications. ACS Chem Biol. 2023.

  3. Stanton BZ*, Chory EJ*, Crabtree GR. Chemically induced proximity in biology and medicine. Science. 2018.

Additional Post-doctoral Publications

  1. Zhao EM, Mao AS, de Puig H, Zhang K, Tippens ND, Tan X, Ran FA, Han I, Nguyen PQ, Chory EJ, Hua TY, Ramesh P, Thompson DB, Oh CY, Zigon ES, English MA, Collins JJ. RNA-responsive elements for eukaryotic translational control. Nat Biotechnol. 2022.

  2. Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. A Deep Learning Approach to Antibiotic Discovery. Cell. 2020.

Graduate Publications

  1. Chory EJ, Kirkland JG, Chang CY, D'Andrea VD, Gourisankar S, Dykhuizen EC, Crabtree GR. Chemical Inhibitors of a Selective SWI/SNF Function Synergize with ATR Inhibition in Cancer Cell Killing. ACS Chem Biol. 2020.

  2. Chory EJ, Calarco JP, Hathaway NA, Bell O, Neel DS, Crabtree GR. Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome. Mol Cell. 2019.

  3. Chory EJ*, Divakaran S*, Bradner JE, & Crabtree GR. A high-throughput platform for assessing synergy of drug combinations.

  4. Braun SMG, Kirkland JG, Chory EJ, Husmann D, Calarco JP, Crabtree GR. Rapid and reversible epigenome editing by endogenous chromatin regulators. Nat Commun. 2017.

  5. Kadoch C, Williams RT, Calarco JP, Miller EL, Weber CM, Braun SM, Pulice JL, Chory EJ, Crabtree GR. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nat Genet. 2017.

Other Publications

  1. Yi JS, Federation AJ, Qi J, Dhe-Paganon S, Hadler M, Xu X, St Pierre R, Varca AC, Wu L, Marineau JJ, Smith WB, Souza A, Chory EJ, Armstrong SA, Bradner JE. Structure-guided DOT1L probe optimization by label-free ligand displacement. ACS Chem Biol. 2015.

  2. Yu W, Chory EJ, Wernimont AK, Tempel W, Scopton A, Federation A, Marineau JJ, Qi J, Barsyte-Lovejoy D, Yi J, Marcellus R, Iacob RE, Engen JR, Griffin C, Aman A, Wienholds E, Li F, Pineda J, Estiu G, Shatseva T, Hajian T, Al-Awar R, Dick JE, Vedadi M, Brown PJ, Arrowsmith CH, Bradner JE, Schapira M. Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun. 2012.

  3. Vickers DA, Chory EJ, Harless MC, Murthy SK. p38 signaling and receptor recycling events in a microfluidic endothelial cell adhesion assay. PLoS One. 2013.

  4. Vickers DA, Chory EJ, Murthy SK. Separation of two phenotypically similar cell types via a single common marker in microfluidic channels. Lab Chip. 2012.